South America cruise
Destination

South America Cruises

1,626 sailings · from $70 per person · rates refreshed daily

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Next South America departures

DepartureShipItineraryLengthFrom portFrom*
Jul 21, 2026 National Geographic Islander II Galápagos Escape - Roundtrip Quito 7 day 6 nights Guayaquil, Ecuador $11,417
Jul 21, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route 6 nights Quito on request
Jul 21, 2026 MS Santa Cruz II Galápagos Islands Expedition Cruise Nine of the Best Isles (Western and Northern Route) 10 nights Quito on request
Jul 23, 2026 Delfin III Exploring Peru: Machu Picchu and the Amazon 8 nights Lima on request
Jul 24, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $18,074
Jul 24, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $10,404
Jul 24, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $20,332
Jul 24, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $12,662
Jul 24, 2026 MS Santa Cruz II Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu 13 nights Lima, Peru on request
Jul 25, 2026 Delfin II Upper Amazon: A River Expedition 8 nights Lima $1,536
Jul 25, 2026 MS Santa Cruz II Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route 6 nights Lima, Peru on request
Jul 25, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama on request
Jul 26, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia on request
Jul 26, 2026 Celebrity Flora 7 Night Galapagos Outer Loop Cruise 7 nights Baltra (Galapagos) on request
Jul 27, 2026 Delfin III Upper Amazon: A River Expedition 5 nights Lima on request
Jul 27, 2026 Delfin III Exploring Peru: Machu Picchu and the Amazon 8 nights Lima on request
Jul 29, 2026 AmaMelodia Wonders of Colombia 7 nights Cartagena, Colombia on request
Jul 29, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu 11 nights Quito on request
Jul 29, 2026 MS Santa Cruz II Galápagos Islands - In Darwin’s Footsteps (Eastern Route) 8 nights Quito on request
Jul 30, 2026 National Geographic Islander II Peru and Galápagos Escape - Lima to Quito 10 nights Lima on request
Jul 30, 2026 MS Santa Cruz II Galápagos Islands - Nine of the Best Isles plus Machu Picchu 15 nights Lima, Peru on request
Jul 31, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $18,800
Jul 31, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $11,250
Jul 31, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $18,920
Jul 31, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $11,130
Aug 1, 2026 Delfin II Upper Amazon: A River Expedition 8 nights Lima on request
Aug 1, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama on request
Aug 2, 2026 Celebrity Flora 7 Night Galapagos Inner Loop Cruise 7 nights Baltra (Galapagos) on request
Aug 2, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia $1,601
Aug 4, 2026 MS Santa Cruz II Galápagos Islands Expedition Cruise Nine of the Best Isles (Western and Northern Route) 10 nights Quito on request
Aug 4, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route 6 nights Quito on request
Aug 4, 2026 National Geographic Islander II Galápagos Escape - Roundtrip Quito 7 day 6 nights Guayaquil, Ecuador $12,193
Aug 7, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $11,227
Aug 7, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $18,897
Aug 7, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $13,147
Aug 7, 2026 MS Santa Cruz II Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu 13 nights Lima, Peru on request
Aug 7, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $20,817
Aug 8, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama $2,721
Aug 8, 2026 Delfin II Upper Amazon: A River Expedition 8 nights Lima on request
Aug 8, 2026 MS Santa Cruz II Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route 6 nights Lima, Peru on request
Aug 9, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia $1,387
Aug 9, 2026 Celebrity Flora 7 Night Galapagos Outer Loop Cruise 7 nights Baltra (Galapagos) on request
Aug 12, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu 11 nights Quito on request
Aug 12, 2026 MS Santa Cruz II Galápagos Islands - In Darwin’s Footsteps (Eastern Route) 8 nights Quito on request
Aug 12, 2026 AmaMelodia Wonders of Colombia 7 nights Cartagena, Colombia $2,899
Aug 13, 2026 MS Santa Cruz II Galápagos Islands - Nine of the Best Isles plus Machu Picchu 15 nights Lima, Peru on request
Aug 13, 2026 Delfin III Exploring Peru: Machu Picchu and the Amazon 8 nights Lima on request
Aug 13, 2026 National Geographic Islander II Peru and Galápagos Escape - Lima to Quito 10 nights Lima on request
Aug 14, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $9,385
Aug 14, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $19,349
Aug 14, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $17,055
Aug 14, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $11,679
Aug 15, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama $1,076
Aug 16, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia $1,731
Aug 16, 2026 Celebrity Flora 7 Night Galapagos Inner Loop Cruise 7 nights Baltra (Galapagos) $12,364
Aug 17, 2026 Delfin III Exploring Peru: Machu Picchu and the Amazon 8 nights Lima on request
Aug 17, 2026 Delfin III Upper Amazon: A River Expedition 5 nights Lima on request
Aug 18, 2026 MS Santa Cruz II Galápagos Islands Expedition Cruise Nine of the Best Isles (Western and Northern Route) 10 nights Quito $11,216
Aug 18, 2026 National Geographic Islander II Galápagos Escape - Roundtrip Quito 7 day 6 nights Guayaquil, Ecuador $8,051
Aug 18, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route 6 nights Quito $7,343

*Per person, double occupancy, cruise fare from. Taxes and fees may apply. Rates refresh daily — email us for today's exact price.

Cruise lines sailing to the South America

Lindblad Expeditions · HX Expeditions · Royal Caribbean International · Celebrity Cruises · AmaWaterways · Silversea · Seabourn · Uniworld River Cruises · MSC Cruzeiros · Holland America Line · AIDA Cruises · Aurora Expeditions · Princess Cruises · Ponant · Costa Cruises · Scenic Ocean Cruises · Viking · Regent Seven Seas Cruises · Hapag-Lloyd Cruises · Crystal Cruises · Norwegian Cruise Line · Oceania Cruises · Carnival Cruise Line · Saga Ocean Cruises · Cunard · Azamara · Windstar Cruises

Frequently asked questions

When is the best time for a South America cruise?
South America itineraries run through most of the year; email us and we'll match the season to your dates.

Where do South America cruises depart from?
Main embarkation ports include Guayaquil, Ecuador, Quito, Lima, Lima, Peru, Colon, Panama.

How much does a South America cruise cost?
Fares vary by ship, cabin and date; current sailings start around $70 per person, double occupancy. Rates refresh daily — email us for an exact quote.