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South America cruise
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South America Cruises

3,127 sailings · from $70 per person · rates refreshed daily

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Huma Travel › Cruises › South America
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Next South America departures

DepartureShipItineraryLengthFrom portFrom*
Oct 2, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $17,808
Oct 2, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $25,376
Oct 2, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $17,706
Oct 2, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $10,138
Oct 2, 2026 MS Santa Cruz II Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu 13 nights Lima, Peru $9,925
Oct 2, 2026 National Geographic Delfina Galápagos by Catamaran: An Intimate Voyage 9 nights Guayaquil, Ecuador $28,196
Oct 2, 2026 National Geographic Delfina Galápagos by Catamaran, Machu Picchu and Peru's Land of the Inca 15 nights Quito $35,866
Oct 2, 2026 Delfin III From the Inca Empire to the Peruvian Amazon with the Nazca Lines 12 nights Lima, Peru on request
Oct 3, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama on request
Oct 3, 2026 Silver Origin San Cristóbal, Galapagos to San Cristóbal, Galapag 7 nights San Cristóbal, Galapagos $13,400
Oct 3, 2026 Delfin II Upper Amazon: A River Expedition 8 nights Lima $26,992
Oct 3, 2026 MS Santa Cruz II Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route 6 nights Lima, Peru $5,884
Oct 3, 2026 Aqua Nera Amazon Discovery Cruise 3 nights Iquitos, Peru $5,280
Oct 4, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia on request
Oct 4, 2026 Seabourn Pursuit 32-Day Across Oceanic Cultures: Fiji to the Chilean Coast 32 nights Lautoka, Fiji on request
Oct 4, 2026 Celebrity Flora 7 Night Galapagos Outer Loop Cruise 7 nights Baltra (Galapagos) on request
Oct 4, 2026 Delfin III From the Inca Empire to the Peruvian Amazon 10 nights Lima, Peru on request
Oct 5, 2026 Seabourn Venture 24-Day Southern Caribbean Yacht Harbors & Coast of Brazil 24 nights Halifax, Nova Scotia on request
Oct 7, 2026 AmaMelodia Wonders of Colombia 7 nights Cartagena, Colombia on request
Oct 7, 2026 Aria Amazon Peruvian Rivers & Rainforest Discovery 10 nights Lima on request
Oct 7, 2026 Aria Amazon Peruvian Amazon & Machu Picchu Exploration 15 nights Lima on request
Oct 7, 2026 MS Santa Cruz II Galápagos Islands - In Darwin’s Footsteps (Eastern Route) 8 nights Quito $6,695
Oct 7, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu 11 nights Quito $9,646
Oct 8, 2026 National Geographic Islander II Peru and Galápagos Escape - Lima to Quito 10 nights Lima on request
Oct 8, 2026 MS Santa Cruz II Galápagos Islands - Nine of the Best Isles plus Machu Picchu 15 nights Lima, Peru $13,131
Oct 9, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $17,786
Oct 9, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $26,252
Oct 9, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $10,116
Oct 9, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $18,582
Oct 9, 2026 Delfin III From the Inca Empire to the Peruvian Amazon with the Nazca Lines 12 nights Lima, Peru on request
Oct 10, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama on request
Oct 10, 2026 Silver Origin San Cristóbal, Galapagos to San Cristóbal, Galapag 7 nights San Cristóbal, Galapagos on request
Oct 10, 2026 AmaMagdalena Wonders of Colombia 7 nights Cartagena, Colombia $3,799
Oct 11, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia on request
Oct 11, 2026 Celebrity Flora 7 Night Galapagos Inner Loop Cruise 7 nights Baltra (Galapagos) on request
Oct 11, 2026 Delfin III From the Inca Empire to the Peruvian Amazon 10 nights Lima, Peru on request
Oct 12, 2026 Silver Cloud Papeete (Tahiti) to Valparaiso 23 nights Papeete (Tahiti) $17,900
Oct 13, 2026 Seabourn Venture 16-Day Trinidad to Rio: South American Expedition 16 nights Bridgetown, Barbados $9,624
Oct 13, 2026 MS Santa Cruz II Galápagos Islands - Nine of the Best Isles (Western and Northern Route) 10 nights Quito $9,901
Oct 13, 2026 MS Santa Cruz II Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route 6 nights Quito $6,416
Oct 13, 2026 National Geographic Islander II Galápagos Escape - Roundtrip Quito 7 day 6 nights Guayaquil, Ecuador $9,371
Oct 16, 2026 Seabourn Pursuit 19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers 19 nights Papeete, French Polynesia on request
Oct 16, 2026 National Geographic Endeavour II Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $20,792
Oct 16, 2026 National Geographic Gemini Exploring Galápagos, Machu Picchu and Peru's Land 15 nights Guayaquil, Ecuador $25,487
Oct 16, 2026 National Geographic Gemini Exploring Galápagos 9 nights Guayaquil, Ecuador $17,817
Oct 16, 2026 National Geographic Endeavour II Exploring Galápagos 9 nights Guayaquil, Ecuador $13,122
Oct 16, 2026 MS Santa Cruz II Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu 13 nights Lima, Peru $9,925
Oct 16, 2026 National Geographic Delfina Galápagos by Catamaran: An Intimate Voyage 9 nights Guayaquil, Ecuador $24,572
Oct 16, 2026 National Geographic Delfina Galápagos by Catamaran, Machu Picchu and Peru's Land of the Inca 15 nights Quito $32,242
Oct 17, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Colon, Panama on request
Oct 17, 2026 Silver Origin San Cristóbal, Galapagos to San Cristóbal, Galapag 7 nights San Cristóbal, Galapagos on request
Oct 17, 2026 Silver Origin San Cristóbal, Galapagos to San Cristóbal, Galapag 14 nights San Cristóbal, Galapagos on request
Oct 17, 2026 Delfin II Upper Amazon: A River Expedition 8 nights Lima $26,992
Oct 17, 2026 MS Fridtjof Nansen Chilean Fjords – Discovering the Heart of Patagonia Southbound 14 nights Valparaiso $6,318
Oct 17, 2026 MS Santa Cruz II Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route 6 nights Lima, Peru $6,416
Oct 17, 2026 Aqua Nera Amazon Discovery Cruise 3 nights Iquitos, Peru $5,620
Oct 18, 2026 Grandeur of the Seas 7 Night Southern Caribbean Cruise 7 nights Cartagena, Colombia $3,906
Oct 18, 2026 Nieuw Amsterdam 21-Day Panama Canal & Southern Caribbean: Abc Islands 21 nights Fort Lauderdale on request
Oct 18, 2026 Nieuw Amsterdam 12-Day Panama Canal Discovery: Costa Rica & Greater Antilles 12 nights Fort Lauderdale $2,324
Oct 18, 2026 AIDAsol From Hamburg to Sydney 74 nights Hamburg on request

*Per person, double occupancy, cruise fare from. Taxes and fees may apply. Rates refresh daily — email us for today's exact price.

Cruise lines sailing to the South America

Lindblad Expeditions
772 South America sailings
HX Expeditions
290 South America sailings
Avalon Waterways
63 South America sailings
Royal Caribbean International
90 South America sailings
Silversea
230 South America sailings
Aqua Expeditions
426 South America sailings
Seabourn
76 South America sailings
Celebrity Cruises
119 South America sailings
AmaWaterways
55 South America sailings
Uniworld River Cruises
50 South America sailings
Holland America Line
73 South America sailings
AIDA Cruises
2 South America sailings

Frequently asked questions

When is the best time for a South America cruise?
South America itineraries run through most of the year; request a quote and we'll match the season to your dates.

Where do South America cruises depart from?
Main embarkation ports include Guayaquil, Ecuador, Lima, Peru, Quito, Colon, Panama, San Cristóbal, Galapagos.

How much does a South America cruise cost?
Fares vary by ship, cabin and date; current sailings start around $70 per person, double occupancy. Rates refresh daily — request a quote for an exact price.